ODCs

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1 OMIM reference -
1 associated gene
10 signs/symptoms

PROTEIN INTERACTIONS: 1
COMMON SIGNS: 3

1 OMIM reference -
1 associated gene
9 signs/symptoms

Testicular regression syndrome

Partial androgen insensitivity syndrome


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	SRY	(0.87)	AR

Citations in the biomedical literature:

Testicular regression syndrome		Partial androgen insensitivity syndrome
	Synonym(s): - ETRS - Embryonic testicular regression syndrome - TRS - Vanishing testes syndrome - Vanishing testis syndrome		Synonym(s): - PAIS - Partial androgen resistance syndrome

	Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare endocrine disease - Rare genetic disease - Rare infertility - Rare urogenital disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare endocrine disease - Rare genetic disease - Rare gynecologic or obstetric disease - Rare infertility - Rare urogenital disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Endocrine, nutritional and metabolic diseases -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: childhood Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: normal Type of inheritance: x-linked recessive

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - No MeSH references


COMMON SIGNS	- Micropenis / small penis / agenesis - Sterility / hypofertility - Uterine / uterus / Fallopian tubes anomalies

Testicular regression syndrome		Partial androgen insensitivity syndrome
	Very frequent - Ambiguous genitalia - Autosomal recessive inheritance - Late puberty / hypogonadism / hypogenitalism - Male internal genitalia anomaly / deferent ducts agenesis / ectopy / duplication - Male pseudohermaphrodism / lack of virilisation - Small / atrophic / hypoplastic testes / monorchism / microorchidism / anorchia Occasional - Face / facial anomalies		Very frequent - Bifid scrotum - Hypospadias / epispadias / bent penis Frequent - Female pseudohermaphrodism / virilisation / clitoridomegaly - Testicular / seminal neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma) Occasional - Gynecomastia / breast / mammary gland enlargement / hyperplasia - Osteoporosis / osteopenia / demineralisation / osteomalacia / rickets